49ers achieve 41-17 victory over Chargers in preseason game
Yahoo Sports • 1 min read • Latest: Aug 21, 2026, 11:04 AM
Last updated Aug 21, 2026

The San Francisco 49ers secured a 41-17 win against the Los Angeles Chargers on August 21 during Week 2 of the NFL preseason. Key performances included rookie De'Zhaun Stribling, who caught four passes for 46 yards, and Jacob Cowing's 83-yard punt return for a touchdown. Brock Purdy displayed command of the offense, going four-for-six for 29 yards. The 49ers are preparing for their regular season opener against the Los Angeles Rams in three weeks. Roster decisions, particularly at running back and left guard, will be closely monitored as the preseason progresses.
- •49ers beat Chargers 41-17 in Week 2 of preseason
- •De'Zhaun Stribling totals 109 receiving yards in two preseason games
- •Jacob Cowing scores on an 83-yard punt return
- •Brock Purdy completes four passes, demonstrating offensive command
- •Roster decisions remain for running backs and left guard positions.
- 11:04 AMYahoo Sports — 7 things that stood out in 49ers blowout preseason win over Chargers
"There was plenty to learn from the San Francisco 49ers' blowout win over the Los Angeles Chargers in Week 2 of the preseason.
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