49ers and Seahawks face off as both teams seek victory in Seattle

The San Francisco 49ers travel to Lumen Field to face the Seattle Seahawks in an NFC West clash on October 10, 2026. The 49ers enter the matchup with a perfect 4-0 record, while the Seahawks sit at 3-1 after a loss to the Washington Commanders in Week 3. Both teams have shown strong performances early in the season, with San Francisco boasting the top offense in the league and Seattle being solid defensively. The outcome of this game could impact the division standings moving forward.

• 4:43 PMYahoo Sports — NFL predictions: 49ers and Seahawks feel like a low-scoring game