49ers defensive lineman James Thompson Jr. suffers ankle injury against Dolphins
Yahoo Sports • 1 min read • Latest: Sep 20, 2026, 10:26 PM
Last updated Sep 20, 2026

During the third quarter of their Week 2 game against the Miami Dolphins at Levi's Stadium, San Francisco 49ers rookie defensive lineman James Thompson Jr. suffered an ankle injury. He walked off the field under his own power but was questionable to return. The 49ers already faced injury challenges with Alfred Collins and Mykel Williams on injured reserve, leaving Osa Odighizuwa, C.J. West, and Gracen Halton to fill in the defensive line if Thompson is unable to return. The game is ongoing.
- •James Thompson Jr. injured in the third quarter against Miami
- •Thompson walked off the field but is questionable to return
- •49ers defensive line already impacted by injuries to Collins and Williams
- •Ongoing game at Levi's Stadium
- 10:26 PMYahoo Sports — 49ers rookie suffers ankle injury in third quarter vs. Dolphins
"The San Francisco 49ers continue to deal with some serious injury issues, especially int he defensive line room.
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