49ers face injury challenges with multiple players on IR going into Week 2

The San Francisco 49ers are managing a significant injury list as they enter Week 2 of the NFL season. Currently, 13 players are on Injured Reserve (IR), including De'Zhaun Stribling, who is expected to undergo ankle surgery. Other notable players on IR include WR Christian Kirk and OL Austen Pleasants, both eligible to return after Week 4. While the team is keeping options open for players like CB Nate Hobbs, the recovery timelines for injured players vary significantly. Coach Kyle Shanahan acknowledges potential long-term absences for several players, including DL Alfred Collins and DL Mikail Kamara, who will not return this season.

• 3:00 AMYahoo Sports — 49ers injury updates: Which players on IR can or will return in 2026?