49ers improve to 3-0 despite injuries during win over Cardinals

Yahoo Sports • 1 min read • Latest: Sep 28, 2026, 1:34 AM

Last updated Sep 28, 2026

49ers improve to 3-0 despite injuries during win over Cardinals
Summary

The San Francisco 49ers topped the Arizona Cardinals, 36-30, on September 27 at Levi's Stadium. The 49ers established an early lead, going into halftime ahead 17-6. Despite a strong fourth-quarter surge from the Cardinals, in which they outscored the 49ers 17-13, San Francisco held on for the victory. However, the win was costly, as the 49ers lost multiple players to injury, including top receiver Mike Evans and left tackle Trent Williams. George Kittle's two touchdowns tied him for the most receiving touchdowns in franchise history.

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Status Watch
  • •49ers lead 17-6 at halftime before Cardinals rally in the fourth quarter.
  • •George Kittle catches six passes for two touchdowns.
  • •Mike Evans and Trent Williams exit the game due to injuries.
  • •Brock Purdy throws for 297 yards and four touchdowns.
  • •49ers defense gives up 30 points, their worst outing so far.
Latest Updates
  • 1:34 AMYahoo Sports — San Francisco 49ers rolling but lose players in win vs Cardinals
What they're saying
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San Francisco 49ers took care of the Arizona Cardinals but lost a couple players in the process, a familiar storyline.

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