49ers report eight players did not practice ahead of Week 3 matchup

Yahoo Sports1 min read • Latest: Sep 24, 2026, 3:44 AM

Last updated Sep 24, 2026

49ers report eight players did not practice ahead of Week 3 matchup
Summary

The San Francisco 49ers have listed eight players on their injury report following Wednesday's practice as they prepare for their Week 3 game against the Arizona Cardinals. Notable absences include defensive end Nick Bosa, wide receiver Mike Evans, and running back Christian McCaffrey, all listed as not participating. The team also placed defensive tackle C.J. West on injured reserve due to a knee injury, raising concerns about depth at the position. Head coach Kyle Shanahan confirmed efforts to bolster the defensive line through a new signing and players on the practice squad. The Arizona Cardinals also released an injury report, with four players missing practice, including nose tackle Roy Lopez and cornerback Max Melton.

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Status Watch
  • C.J. West placed on injured reserve with a knee injury.
  • Nick Bosa, Mike Evans, and Christian McCaffrey did not practice.
  • Four Cardinals players, including Roy Lopez, were listed as DNP.
  • San Francisco signed Naquan Jones from the Vikings practice squad.
  • Both teams are preparing for their Week 3 game against each other.
Latest Updates
  • 3:44 AMYahoo Sports49ers injury report: 8 sit out Wednesday
What they're saying
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See which 49ers players didn't practice or were limited on Wednesday.

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