49ers seek 3-0 start against Cardinals without Nick Bosa

The San Francisco 49ers are set to face the Arizona Cardinals on Sunday in search of their third consecutive victory of the season. The team will play without defensive end Nick Bosa, raising questions about the depth of their defense. San Francisco's offensive strategies may hinge on the team's backup quarterback, Mac Jones, whose trade value has been highlighted amid a wave of quarterback injuries across the league. Analysts suggest the 49ers should carefully consider potential trade offers, given his importance if starter Brock Purdy faces injury again. Meanwhile, the performances of receivers Deebo Samuel and linebacker Dre Greenlaw have been promising, reassuring fans about their roles despite past concerns about their fitness.

• 9:56 PMYahoo Sports — 49ers-Cardinals: Can defense cope without Nick Bosa? Should Mac Jones be traded?