League: NFL Sport: Football Country: United States Category: Injuries

49ers WR Deebo Samuel ruled out with hamstring injury

4 sources • 1 min read • Latest: Oct 12, 2026, 12:02 AM

Last updated Oct 12, 2026

49ers WR Deebo Samuel ruled out with hamstring injury

Summary

Deebo Samuel of the 49ers has been ruled out with a hamstring injury sustained during a running play on October 11. The injury occurred as he attempted to maneuver around the corner, resulting in a lost fumble. Following Samuel's injury, the Seahawks capitalized, leading the game 26-21. Additionally, Jacob Cowing of the 49ers is questionable to return due to an ankle injury, leaving the team with limited receiving options.

Source Links

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Status Watch

•Deebo Samuel injured his hamstring on a running play.
•Samuel has two catches for 21 yards and one fumble.
•The Seahawks lead the game 26-21 after the injury.
•Jacob Cowing is questionable with an ankle injury.
•Mike Evans, Brandin Cooks, and Jordan Watkins are the remaining healthy receivers.

Latest Updates

12:14 AMESPN NFL — 49ers WR corps hit again as Samuel ruled out with hamstring injury
11:52 PMYahoo Sports — Deebo Samuel injury update: Latest on 49ers WR's status in Week 5 game
11:24 PMYahoo Sports — 49ers WR Deebo Samuel leaves game with hamstring injury
11:02 PMYahoo Sports — 49ers WR Deebo Samuel ruled out with hamstring injury

What they're saying

"
SEATTLE (AP) — San Francisco 49ers wide receiver Deebo Samuel was ruled out of Sunday’s game against the Seattle Seahawks with a hamstring injury after he left the field late in the third quarter.Samuel fumbled at the 49ers 35 and was motionless on the field for several seconds before limping to the sideline.
— Yahoo Sportsby SHANE LANTZ

"
The 49ers ruled out Deebo Samuel due to a hamstring injury in the third quarter, leaving San Francisco with just three healthy wideouts to finish Sunday's game vs. the Seahawks.
— ESPN NFLby Nick Wagoner