Arizona Cardinals fall to Detroit Lions, 45-21, in Week 5 matchup

The Arizona Cardinals faced the Detroit Lions on October 12, 2026, suffering a 45-21 loss. The team recorded 73 offensive snaps, with quarterback Jacoby Brissett completing 47 passes for 292 yards and three touchdowns, although much of this production came during the second half after the game was largely out of reach. The Cardinals struggled with a limited ground game, as running backs Jeremiyah Love and Tyler Allgeier combined for just 53 yards on 28 carries. Head coach Mike LaFleur addressed the team's overall performance, indicating that many issues needed correction, but stated that the quarterback was not at fault. The Cardinals now turn their focus to improving their offensive unit ahead of the next game.

• 3:42 AMYahoo Sports — Arizona Cardinals Week 5 offensive snap counts, observations vs. Lions