Big Ten football Week 4 features key games for USC and Oregon
Yahoo Sports • 1 min read • Latest: Sep 25, 2026, 10:45 AM
Last updated Sep 25, 2026

Week 4 of the college football season sees Big Ten teams in critical matchups on September 25, 2026. USC faces Oregon in a significant clash that will test its current form. Other notable games include Indiana playing Northwestern, and Ohio State taking on Illinois. Each team comes into this week looking to secure wins as conference play intensifies, with Indiana aiming to maintain its home winning streak under head coach Curt Cignetti. The outcomes of these games could have implications for conference rankings moving forward.
- •USC to play Oregon in a key matchup.
- •Indiana seeks to continue home winning streak.
- •Ohio State aims to finish strong against Illinois.
- •Michigan plays Iowa as part of its undefeated season.
- •Penn State faces Wisconsin amid coaching pressure for Fickell.
- 10:45 AMYahoo Sports — Picking every Big Ten game in college football Week 4
"Who do we have winning in the Big Ten this week, including in USC’s massive battle against Oregon?
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