Buffalo Bills open 2026 NFL season against Houston Texans on the road

The Buffalo Bills begin their 2026 NFL campaign with a road game against the Houston Texans. Buffalo enters the matchup looking to end a six-game losing streak at the venue dating back to November 19, 2006. Since that last victory, the Bills have suffered six consecutive losses in Houston, including four during the tenure of Josh Allen. Allen is currently 0-4 in games played at the stadium. The historical stretch includes a 2019 postseason defeat and several narrow regular-season losses, most recently a 23-19 result in 2025. The teams are scheduled to face off as part of the league's opening week slate.

• 10:00 AMYahoo Sports — Last time Buffalo Bills won in Houston, the Nintendo Wii had just been released