Cardinals host Seahawks in key Week 2 matchup on September 20
Yahoo Sports • 1 min read • Latest: Sep 18, 2026, 12:06 PM
Last updated Sep 18, 2026

The Arizona Cardinals will face the Seattle Seahawks on September 20 at State Farm Stadium in Glendale, Arizona. Both teams enter the game with a 1-0 record, but the Cardinals are underdogs due to recent history, having lost nine straight to Seattle. A key factor for Arizona is the injury to Seahawks quarterback Sam Darnold, allowing backup Drew Lock to start. The Cardinals hope to capitalize on this situation while improving their run blocking and defensive performance to secure a win.
- •Game scheduled for September 20 at 1:25 p.m. MST.
- •Cardinals have lost nine consecutive games to the Seahawks.
- •Drew Lock will start for Seattle after Darnold's injury.
- •Arizona's offensive success relies on effective use of three wide receiver sets.
- •Last Cardinals win against Seahawks was in November 2021.
- 1:23 PMYahoo Sports — Arizona Cardinals Daily Links: Are the Seahawks on upset alert?
- 12:06 PMYahoo Sports — The Arizona Cardinals will upset the Seahawks in Week 2. Here's why
"The Arizona Cardinals enter Week 2 as underdogs against the Seattle Seahawks, but Sam Darnold's hip injury gives them a chance of moving to 2-0.
"Are the Cardinals putting the Seahawks on upset alert in Week Two?
Sources
External links- Yahoo SportsSep 18, 2026, 1:23 PMArizona Cardinals Daily Links: Are the Seahawks on upset alert?
Are the Cardinals putting the Seahawks on upset alert in Week Two?
- Yahoo SportsSep 18, 2026, 12:06 PMThe Arizona Cardinals will upset the Seahawks in Week 2. Here's why
The Arizona Cardinals enter Week 2 as underdogs against the Seattle Seahawks, but Sam Darnold's hip injury gives them a chance of moving to 2-0.
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