Chargers face 49ers in preseason matchup tonight
Yahoo Sports • 1 min read • Latest: Aug 21, 2026, 12:00 AM
Last updated Aug 21, 2026
The Los Angeles Chargers are set to face the San Francisco 49ers tonight in their second preseason game. Key details include the interior offensive line's performance, especially with rookie center Jake Slaughter stepping in for the injured Tyler Biadasz. Rookie safety Genesis Smith will also be watched for his ability to continue impactful play in the secondary. Chargers' starters, including quarterback Justin Herbert, will get one series before the backups take over, with a focus on how the team transitions into the upcoming regular season.
- •Game is set for tonight during the second week of preseason
- •Rookie Jake Slaughter replaces injured center Tyler Biadasz
- •Focus on rookie safety Genesis Smith's development
- •Starters expected to play only the first series
- •Quarterback Justin Herbert's performance in new offensive system is critical
- 12:00 AMYahoo Sports — Three Things to Watch as the Chargers Take on the 49ers Tonight
"As the Los Angeles Chargers prepare to take on the San Francisco 49ers in the second week of the preseason, here are three key things to watch.
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