Chargers prepare for challenge against Bills in Week 3 matchup
Yahoo Sports • 1 min read • Latest: Sep 25, 2026, 1:50 PM
Last updated Sep 25, 2026

The Los Angeles Chargers face the Buffalo Bills at Highmark Stadium on September 25, 2026. The Chargers enter the game with a struggling offense, averaging 14.0 points per game, while the Bills boast an impressive 38.5 points per game. This Week 3 contest comes after the Chargers seek to turn around their performance during a tough start to the season at 0-2. Analysts have speculated about the potential for an upset, citing the unpredictable nature of the NFL.
- •Chargers' offense struggles at 14.0 points per game.
- •Bills are 2-0, scoring 38.5 points per game.
- •The game is scheduled for September 25, 2026.
- •Analyzed potential for an upset amid Chargers' rough start.
- •Highmark Stadium hosts the matchup.
- 1:50 PMYahoo Sports — Los Angeles Chargers news: Chargers-Bills final score predictions
"Can Justin Herbert and the Chargers pull off the unlikely upset against the Bills in Week 3?
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