Chargers release first injury report before Sunday matchup against Cardinals
9 sources • 2 min read • Latest: Sep 27, 2026, 5:20 PM
Last updated Sep 27, 2026

The Chargers released their initial injury report on Wednesday ahead of their Week 1 game against the Cardinals. EDGE Khalil Mack and CB Deane Leonard were the only two players who did not participate in practice. Mack was sidelined for rest, while Leonard is managing an abdominal injury. Several other players were listed as limited participants, including S RJ Mickens with an ankle issue, RB Keaton Mitchell with a hamstring injury, and both WR Brenen Thompson and EDGE Tuli Tuipulotu with hip injuries. Mitchell participated in a limited capacity, which follows a period of missed practices due to an undisclosed issue. Despite the injuries, head coach Jim Harbaugh stated he expects offensive tackle Rashawn Slater to be available to play on Sunday.
- •Khalil Mack and Deane Leonard did not practice on Wednesday.
- •Rashawn Slater is expected to play on Sunday despite a knee injury.
- •Keaton Mitchell returned to practice in a limited capacity.
- •Four players including RJ Mickens and Tuli Tuipulotu were listed as limited participants.
- 5:20 PMYahoo Sports — Bills injuries 2026: In-game updates vs. Chargers
- 10:49 PMYahoo Sports — Bills Week 3 injury report vs. Chargers: What it means for fantasy football
- 10:45 AMYahoo Sports — Bills vs. Chargers: Final injury reports for both teams
- 10:45 AMYahoo Sports — Bills vs. Chargers: Thursday injury reports for both teams
- 9:50 PMYahoo Sports — Chargers Thursday injury report of Week 3: 7 players did not practice
- 3:41 PMYahoo Sports — Bills have longest injury report of season, but Chargers' is even longer
- 10:30 PMYahoo Sports — Chargers-Bills Injury Report: Bolts have a laundry list to open Week 3
- 10:24 PMYahoo Sports — Chargers first injury report of Week 3: 8 players did not practice
"Buffalo looks to improve to 3-0 against Los Angeles, but a slew of question marks at the wide receiver position could drastically impact your fantasy lineup The Buffalo Bills are looking to ride the momentum of their undefeated 2-0 start as they prepare to host the winless Los Angeles Chargers at Highmark Stadium on Sunday afternoon. The Bills have […] The post Bills Week 3 injury report vs. Chargers: What it means for fantasy football appeared first on ClutchPoints.
"The Chargers hit the field for their first practice of Bills week and it has unfortunately come with a rather lengthy injury report. In all, 14 players grace the list with two of them being Khalil Mack and Derwin James who received veteran days off. James has a fractured pinky, but the plan is for […]
"The Los Angeles Chargers had another lengthy injury report as they continued their preparation for the Week 3 game against the Buffalo Bills.
Sources
External links- Yahoo SportsSep 27, 2026, 5:20 PMBills injuries 2026: In-game updates vs. Chargers
A thread of injuries as they happen during the Buffalo Bills 2026 Week 3 matchup with the Los Angeles Chargers.
- Yahoo SportsSep 26, 2026, 10:49 PMBills Week 3 injury report vs. Chargers: What it means for fantasy football
Buffalo looks to improve to 3-0 against Los Angeles, but a slew of question marks at the wide receiver position could drastically impact your fantasy lineup The Buffalo Bills are looking to ride the momentum of their undefeated 2-0 start as they prepare to host the winless Los Angeles Chargers at Highmark Stadium on Sunday afternoon. The Bills have […] The post Bills Week 3 injury report vs. Chargers: What it means for fantasy football appeared first on ClutchPoints.
- Yahoo SportsSep 26, 2026, 10:45 AMBills vs. Chargers: Final injury reports for both teams
Here are the final injury reports for both the Bills and Chargers in Week 3.
- Yahoo SportsSep 25, 2026, 10:45 AMBills vs. Chargers: Thursday injury reports for both teams
Here are the latest injury reports for both the Bills and Chargers.
- Yahoo SportsSep 24, 2026, 9:50 PMChargers Thursday injury report of Week 3: 7 players did not practice
The Los Angeles Chargers had another lengthy injury report as they continued their preparation for the Week 3 game against the Buffalo Bills.
- Yahoo SportsSep 24, 2026, 3:41 PMBills have longest injury report of season, but Chargers' is even longer
The Bills listed 10 players on their first Week 3 injury report. The Chargers had 14, including eight who did not practice.
- Yahoo SportsSep 23, 2026, 10:30 PMChargers-Bills Injury Report: Bolts have a laundry list to open Week 3
The Chargers hit the field for their first practice of Bills week and it has unfortunately come with a rather lengthy injury report. In all, 14 players grace the list with two of them being Khalil Mack and Derwin James who received veteran days off. James has a fractured pinky, but the plan is for […]
- Yahoo SportsSep 23, 2026, 10:24 PMChargers first injury report of Week 3: 8 players did not practice
The Los Angeles Chargers had a lengthy injury report as they opened practice ahead of their Week 3 game against the Buffalo Bills.
- Yahoo SportsSep 9, 2026, 10:32 PMChargers' first injury report of Week 1: 2 players did not practice
Khalil Mack and Deane Leonard were the only Chargers players who did not practice on Wednesday.
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