Detroit Lions dominate Arizona Cardinals 45-21 in Week 5 matchup
Yahoo Sports • 1 min read • Latest: Oct 13, 2026, 11:30 AM
Last updated Oct 13, 2026

The Detroit Lions secured a decisive 45-21 victory over the Arizona Cardinals on October 11, 2026, in Glendale, Arizona. After trailing 7-0 early in the game, the Lions responded with a 31-0 run, highlighted by 24 points in the second quarter. Key performances included tight end Sam LaPorta, who recorded five catches for 88 yards, and left tackle Penei Sewell, who did not allow any pressures. This game serves as a pivotal moment for the Lions as they head into their bye week before facing divisional rivals in upcoming matchups.
- •Lions scored 31 unanswered points after an early deficit.
- •Sam LaPorta finished with five catches for 88 receiving yards.
- •Penei Sewell excelled in pass protection without allowing pressures.
- •Lions head into a bye week before divisional games.
- 11:30 AMYahoo Sports — Detroit Lions stock report: 20 risers, 3 fallers against the Cardinals
"The biggest risers and fallers from the Detroit Lions’ feather-flying plucking of the Arizona Cardinals
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