Falcons hand 49ers first loss of season in 29-20 defeat
Yahoo Sports • 1 min read • Latest: Oct 25, 2026, 9:01 PM
Last updated Oct 25, 2026

The San Francisco 49ers lost to the Atlanta Falcons 29-20 on October 25, marking their first defeat of the 2026 season. After leading 14-3, the 49ers struggled with turnovers and penalties, allowing the Falcons to score 23 unanswered points. Quarterback Brock Purdy became a critical factor, throwing two interceptions, one of which sealed the game for Atlanta. San Francisco now faces a bye week, needing to address issues in special teams and injuries, to running back Christian McCaffrey, who sustained a quad injury during the game.
- •49ers fell from a 14-3 lead, allowing 23 consecutive points.
- •Brock Purdy completed 27 of 40 passes for 288 yards.
- •San Francisco turned the ball over four times, including two fumbles.
- •The 49ers received seven penalties for 55 yards during the game.
- •Christian McCaffrey's status is uncertain due to a quad injury.
- 9:01 PMYahoo Sports — 9 takeaways from 49ers' worst performance of 2026
"The San Francisco 49ers couldn't have been a lot worse in their first loss of the season vs. the Atlanta Falcons. We had a bunch of takeaways.
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