Houston Texans host Buffalo Bills in NFL season opener at Reliant Stadium

The Buffalo Bills travel to Houston to face the Texans this Sunday, September 13, at 1 p.m. ET. The Week 1 matchup at Reliant Stadium features a contest between the Bills' offense and the Texans' defense. Tickets for the game remain available for purchase, with prices starting at $110 for the lowest-priced seats. Limited lower-level tickets are also being offered as the teams begin their 2026 campaigns. Following this weekend's opener, both franchises continue their regular season schedules with Week 2 contests scheduled for next week. The Bills are set to return home to host the Detroit Lions, while the Texans will play host to the Cincinnati Bengals.

• 8:28 PMYahoo Sports — How to buy Buffalo Bills vs Houston Texans Week 1 NFL tickets