Injuries challenge fantasy football lineups ahead of Week 4 matches

Yahoo Sports • 1 min read • Latest: Oct 3, 2026, 6:47 PM

Last updated Oct 3, 2026

Injuries challenge fantasy football lineups ahead of Week 4 matches
Summary

As Week 4 of the NFL approaches, key players including Justin Jefferson, DeVonta Smith, and Breece Hall have been ruled out due to injuries. The latest reports confirm that quarterbacks Caleb Williams, Baker Mayfield, and Jayden Daniels, among others, will also not participate. With many positions affected, fantasy managers are vying for late waiver wire pickups to fill gaps before Sunday and Monday lineups. The injury report highlights additional players out or questionable, further complicating roster decisions ahead of kickoff.

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Status Watch
  • •Justin Jefferson and DeVonta Smith confirmed out for Week 4.
  • •Quarterbacks Caleb Williams and Baker Mayfield will not play.
  • •Fantasy managers face limited waiver wire options.
  • •Injury report includes multiple key players across positions.
  • •Week 4 action starts with several teams affected by injuries.
Latest Updates
  • 6:47 PMYahoo Sports — Fantasy football Week 4 injuries: Late waiver pickups after Justin Jefferson, DeVonta Smith, Breece Hall out
What they're saying
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With Justin Jefferson, DeVonta Smith and Breece Hall ruled out, these players can fill Sunday and Monday lineup holes.

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