Injuries reported ahead of Bills vs. Lions Thursday Night Football
Yahoo Sports • 1 min read • Latest: Sep 14, 2026, 2:39 PM
Last updated Sep 14, 2026

The Buffalo Bills are set to host the Detroit Lions on Thursday Night Football, September 17, at 8:15 p.m. Multiple Bills players are dealing with injuries following a 36-31 win against the Houston Texans, including safety Cole Bishop and linebacker Terrel Bernard. The Lions also face significant injury concerns after a narrow 31-30 victory over the New Orleans Saints, with starting guard Christian Mahogany and center Cade Mays unavailable. The conditions of key defensive players for Detroit, Kerby Joseph and Brian Branch, remain uncertain as they are on the physically unable to perform list.
- •Bills play Lions in the first regular-season game at Highmark Stadium.
- •Cole Bishop faces a left knee injury but is probable to return.
- •Christian Mahogany's injury could affect Lions' offensive line depth.
- •Kerby Joseph and Brian Branch remain on PUP for the Lions.
- 2:39 PMYahoo Sports — Bills vs. Lions injury update: Detroit's offensive line limps into Thursday Night Football
"Here's who might be out when the Bills and Lions play on Thursday Night Football in Week 2.
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