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Lions visit Bills to kick off NFL Week 2 schedule on Thursday

22 sources • 3 min read • Latest: Sep 18, 2026, 5:07 AM

Last updated Sep 18, 2026

Lions visit Bills to kick off NFL Week 2 schedule on Thursday
Summary

The NFL Week 2 schedule begins as the Detroit Lions face the Buffalo Bills on Thursday, September 17, at 8:15 p.m. on Amazon. This matchup marks the start of a packed weekend with several games lined up, including the Cincinnati Bengals at the Houston Texans, and the Philadelphia Eagles at the Tennessee Titans on Sunday. NFL fans can catch all games on various platforms such as CBS, FOX, and Peacock, with options available for streaming through Amazon Prime and Paramount+. Following this week's action, the New York Giants will challenge the Los Angeles Rams on Monday, September 21, at 8:15 p.m. on ABC/ESPN.

Source Links
Yahoo Sports
Status Watch
  • •Lions at Bills, Thursday, Sept. 17, 8:15 p.m. on Amazon
  • •Bengals at Texans and Eagles at Titans on Sunday
  • •Other games include Panthers at Falcons and Steelers at Patriots
  • •Giants face Rams on Monday, Sept. 21, 8:15 p.m. on ABC/ESPN
  • •Games available on CBS, FOX, NBC, and streaming services
Latest Updates
  • 5:07 AMYahoo Sports — Everyone Is Saying the Same Thing About Lions-Bills Game on Thursday Night Football
  • 4:25 AMYahoo Sports — 3 overreactions as Bills thump Lions on 'Thursday Night Football'
  • 3:12 AMYahoo Sports — Thursday Night Football: Winners, Losers from Buffalo Bills’ Statement Win Over Detroit Lions
  • 11:30 PMYahoo Sports — Thursday Night Football live discussion: Lions at Bills
  • 11:27 PMYahoo Sports — Detroit Lions announce inactives vs. Bills in 'Thursday Night Football'
  • 11:00 PMYahoo Sports — Who Are the Lions-Bills Announcers? A Look at Amazon Prime Video Broadcasters for Week 2’s Thursday Night Football Clash
  • 10:55 PMYahoo Sports — Who's playing on Thursday Night Football tonight? Lions vs Bills
  • 10:45 PMYahoo Sports — Lions vs. Bills live updates, inactives, where to watch: Josh Allen, Jared Goff matchup christens new Highmark Stadium on Thursday Night Football
What they're saying
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Week 2 of the 2026 NFL season opens with the first Thursday Night Football game, a matchup between the Detroit Lions and the Buffalo Bills. The game is set to take place at the new Highmark Stadium in Orchard Park, New York, where the Bills QB Josh Allen will face off against Lions QB Jared …

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The Detroit Lions and the Buffalo Bills both survived their Week 1 assignments. The Lions completed a one-point overtime win against the New Orleans Saints after the latter failed to convert a two-point try following a touchdown.

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Two of the NFL’s most explosive offenses take center stage Thursday night when the Detroit Lions visit the Buffalo Bills to kick off Week 2 of the 2026 season. Both teams enter at 1-0 after winning one-score games in Week…

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