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Louisville and Ole Miss prepare for season opener at Nissan Stadium

Yahoo Sports • 1 min read • Latest: Aug 31, 2026, 9:13 AM

Last updated Aug 31, 2026

Louisville and Ole Miss prepare for season opener at Nissan Stadium

Summary

Louisville football is entering its final week of preparation for a September 6 matchup against No. 10 Ole Miss. The game is scheduled for 7:30 p.m. at Nissan Stadium in Nashville. This represents the only AP top-25 clash during the college football season's opening week. Both programs enter the contest with significant roster changes, particularly among receiving corps that have been rebuilt through the transfer portal. Jeff Brohm leads the No. 24 Cardinals, while Pete Golding begins his first full season as head coach for the Rebels. The two teams last met in 2021 when Ole Miss recorded a 43-24 victory in Atlanta.

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By the Numbers

•Louisville and Ole Miss play at 7:30 p.m. on September 6 at Nissan Stadium.
•Ole Miss enters ranked No. 9 in the AP poll and Louisville is ranked No. 24.
•Ole Miss defeated Louisville 43-24 in their only previous meeting in 2021.
•Both teams overhauled their receiving units using the transfer portal during the offseason.
•Louisville running back Isaac Brown returns as a preseason All-American for the opener.

Latest Updates

9:13 AMYahoo Sports — Storylines, players to watch in Louisville vs Ole Miss football opener

What they're saying

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Louisville football has switched from fall camp to game preparation. Here are storylines and players to watch in the Cards' opener against Ole Miss.
— Yahoo Sports

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