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Louisville Cardinals face Syracuse Orange at JMA Wireless Dome

Yahoo Sports • 1 min read • Latest: Oct 17, 2026, 4:00 AM

Last updated Oct 17, 2026

Louisville Cardinals face Syracuse Orange at JMA Wireless Dome

Summary

The Louisville Cardinals (3-3, 2-2) visit the Syracuse Orange (2-3, 0-3) today at 7:30 p.m. ET. The game will be broadcast on the ACC Network. Louisville is favored by 14.5 points with a historical edge in the series, leading 13-8. Syracuse, struggling with injuries at quarterback, will start Malachi Nelson after a series of difficulties with previous starters Steve Angeli and Amari Odom. The last meeting saw Syracuse win 31-7 on September 3, 2022.

Source Links

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Status Watch

•Game time is set for 7:30 p.m. ET.
•Syracuse is on a three-game losing streak.
•Malachi Nelson to start at quarterback for Syracuse.
•Louisville was previously defeated by Syracuse in their last matchup.
•Louisville leads the all-time series 13-8.

Latest Updates

4:00 AMYahoo Sports — Game Day: Louisville at Syracuse

What they're saying

"
LOUISVILLE CARDINALS (3-3, 2-2) at SYRACUSE ORANGE (2-3, 0-3) Game Time: 7:30 p.m. Location: JMA Wireless Dome: Syracuse, N.Y. Television: ACC Network Announcers: Jorge Sedano (play-by-play), Rodney McLeod Jr (analyst), and Annabelle Hasselbeck (sidelines) Favorite: Louisville by 14.5 All-Time Series: Louisville leads, 13-8 Last Meeting: Syracuse won 31-7 on Sept. 3, 2022 in Syracuse Series […]
— Yahoo Sports

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