Louisville football prepares for neutral site matchup against Ole Miss
Yahoo Sports • 1 min read • Latest: Sep 6, 2026, 3:01 PM
Last updated Sep 6, 2026

Louisville and Ole Miss meet in Nashville for a non-conference college football game scheduled for Sunday night. The Cardinals enter the matchup with Isaac Brown available, though the team will be without left tackle Anwar O’Neal and a reserve offensive lineman. Analysts remain divided on the outcome, with some outlets favoring the Rebels by a touchdown while others project a closer contest. The Louisville volleyball program enters the weekend following a sweep of TCU, and the university’s rugby team recently secured a win against Tennessee. Looking ahead, the Louisville men’s basketball program continues preparations for its upcoming schedule while evaluating various high school prospects. The matchup in Nashville serves as the season opener for both programs and represents a significant test for the Cardinals against a ranked opponent.
- •Louisville faces Ole Miss at a neutral site in Nashville on Sunday night.
- •Isaac Brown is healthy for the Cardinals while Anwar O’Neal is ruled out.
- •Ole Miss enters the contest as a betting favorite with various point spreads reported.
- •Louisville volleyball recorded a sweep over No. 18 TCU on Friday.
- •The Louisville rugby team defeated Tennessee on Friday.
- 3:01 PMYahoo Sports — Game day morning Cardinal news and notes
"Running into Jaire Alexander on a pregame hike in Nashville is a vibe setter.
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