NFL predictions highlight key players and potential upsets for weekend games

2 sources • 1 min read • Latest: Sep 26, 2026, 11:32 AM

Last updated Sep 26, 2026

NFL predictions highlight key players and potential upsets for weekend games
Summary

As NFL teams prepare for weekend matchups, predictions suggest potential standout performances from several players. Kenneth Walker III and Xavier Worthy are expected to score touchdowns, while the Denver Broncos may pull off an upset against the Los Angeles Rams. Discussions include the rising fantasy value of C.J. Stroud and expectations for a strong outing from Geno Smith. These predictions come as teams look to solidify their standing in the league during the early season.

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By the Numbers
  • •Kenneth Walker III and Xavier Worthy predicted to score touchdowns.
  • •Denver Broncos may upset the Los Angeles Rams.
  • •C.J. Stroud's fantasy value is rising significantly.
  • •Geno Smith is anticipated to have a strong performance.
Latest Updates
  • 12:11 PMESPN — 15 predictions for this weekend's NFL games: We picked upsets, sleepers, TD scorers and more
What they're saying
"

Touchdowns for Kenneth Walker III and Xavier Worthy? The Broncos pulling an upset of the Rams? Fantasy value for C.J. Stroud? And a big day from Geno Smith?

— ESPNby Matt Bowen, Pamela Maldonado, Eric Moody, Ben Solak and Seth Walder
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