Nick Bosa and Christian McCaffrey miss 49ers practice in Melbourne

The San Francisco 49ers conducted their first open practice in Melbourne, Australia, on Monday ahead of their season-opening game against the Los Angeles Rams. Running back Christian McCaffrey and defensive end Nick Bosa did not participate in the session. McCaffrey spent time on the sideline and participated in individual drills, while Bosa was not present on the field. Head coach Kyle Shanahan confirmed that defensive end Sam Okuayinonu will move to injured reserve after sustaining a broken foot during a practice session on Saturday. The team has signed defensive end Khalid Kareem to the roster to fill the vacancy. Official injury reports are not required from the 49ers until Wednesday morning in Australia, which corresponds to Tuesday night on the West Coast.

• 7:18 AMYahoo Sports — 49ers' Nick Bosa, Christian McCaffrey don't practice; Sam Okuayinonu on IR