Oklahoma State football falls to Houston 35-32 in close Big 12 matchup
2 sources • 1 min read • Latest: Oct 18, 2026, 10:31 AM
Last updated Oct 18, 2026

Oklahoma State lost to Houston 35-32 in a critical Big 12 game on October 17, 2026. The Cowboys, aiming for a top spot in the conference, struggled with turnovers, finishing with a 2-1 disadvantage. Quarterback Drew Mestemaker threw for 365 yards and three touchdowns but also had an interception and two fumbles. Houston's Conner Weigman passed for five touchdowns, capitalizing on Oklahoma State's defensive lapses. The defeat complicates Oklahoma State's hopes for the conference title and the College Football Playoff.
- •Oklahoma State lost to Houston 35-32 on October 17, 2026.
- •Drew Mestemaker had 365 passing yards, three touchdowns, and two turnovers.
- •Houston's Conner Weigman threw for five touchdowns and 343 yards.
- •Oklahoma State's defense allowed 10 of 16 third-and-fourth down conversions.
- •The Cowboys may need to win all remaining games for title hopes.
- 10:31 AMYahoo Sports — Oklahoma State football QB Drew Mestemaker not good enough vs Houston | Report card
"Oklahoma State came to Houston with a chance to stake a claim at one of the top spots in the Big 12. Instead, the Cowboys faltered. Here's how we graded the loss.
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