Ole Miss defeats Louisville in season opener at Nissan Stadium
Yahoo Sports • 1 min read • Latest: Sep 7, 2026, 9:10 AM
Last updated Sep 7, 2026

Ole Miss defeated Louisville 41-38 in Sunday's season opener at Nissan Stadium in Nashville. Despite trailing for portions of the game, the Cardinals maintained a competitive pace, staying within reach of the Rebels until the final whistle. The match served as the first career start for Louisville quarterback Lincoln Kienholz. Head coach Jeff Brohm noted the Cardinals struggled with crowd noise, which led to significant clock mismanagement and the exhaustion of all team timeouts by the end of the third quarter. While running back Isaac Brown faced difficulty finding running lanes against the Ole Miss defense, wide receivers Tre Richardson and Lawayne McCoy provided offensive production through significant scoring plays. Louisville now faces a short week of preparation before hosting Villanova this Friday.
- •Ole Miss defeated Louisville with a final score of 41-38.
- •The game took place at Nissan Stadium in Nashville with 57,390 spectators in attendance.
- •Louisville exhausted all timeouts by the end of the third quarter due to crowd noise.
- •Tre Richardson recorded a 30-yard touchdown run and Lawayne McCoy scored on a 54-yard reception.
- •Louisville plays its next game against Villanova on Friday.
- 9:10 AMYahoo Sports — What we learned from Louisville football's Week 1 loss to Ole Miss
"Louisville football had something to prove to itself and showed it can hang with tougher competition. Here's what we learned from the Week 1 loss.
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