Ole Miss defensive line faces Louisville offensive line in season opener

Yahoo Sports1 min read • Latest: Sep 4, 2026, 1:04 PM

Last updated Sep 4, 2026

Ole Miss defensive line faces Louisville offensive line in season opener
Summary

Ole Miss prepares for its upcoming college football game against Louisville featuring a defensive line anchored by Will Echoles, Kam Franklin, and Jehiem Oatis. Louisville faces the challenge of managing the Rebels' interior pass rush with an offensive line featuring unproven interior players Johnnie Brown and Evan Wibberly alongside Eryx Daughtery. The Rebels offense enters the matchup looking for new production at wide receiver following significant turnover, with Deuce Alexander expected to take on a larger role. On the other side, Louisville running back Isaac Brown serves as a primary offensive focal point for the Cardinals. The game marks the debut of Mark Ivey as play-caller for Louisville under head coach Jeff Brohm. The outcome hinges on whether Louisville can neutralize defensive penetration to open up opportunities for Trinidad Chambliss and Kewan Lacy.

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Key Details
  • Ole Miss features a defensive front led by Will Echoles, Kam Franklin, and Jehiem Oatis.
  • Louisville incorporates new interior starters Johnnie Brown and Evan Wibberly on the offensive line.
  • Deuce Alexander remains the only returning receiver in the Ole Miss rotation from last season.
  • Mark Ivey takes over as the Louisville play-caller for the first time.
  • Isaac Brown returns as the primary rushing threat for the Louisville offense.
Latest Updates
  • 1:04 PMYahoo SportsWhat To Watch For: Ole Miss Rebels
What they're saying
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LOUISVILLE’S INTERIOR OFFENSIVE LINE WILL HAVE THEIR HANDS FULL It seems at times that the great “SEC Defensive Linemen” are mythologized as if they are gods, but I would challenge anyone to watch the highlights of the Ole Miss defensive line and not understand it a little bit. Will Echoles is going to be a […]

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