San Francisco 49ers defeat Los Angeles Rams 27-7 in Melbourne

The San Francisco 49ers defeated the Los Angeles Rams 27-7 on September 11, 2026, at the Melbourne Cricket Ground in Melbourne, Australia. Despite entering the Week 1 contest as three-point underdogs, the 49ers controlled the game behind a defensive performance that produced eight quarterback hits and an interception of Matthew Stafford by Renardo Green. The 49ers' offensive line limited the Rams to zero sacks and two quarterback hits despite the presence of Myles Garrett. Conversely, the Rams failed to produce a sack throughout the game. The loss follows preseason expectations that favored the Rams, including projections that the team would remain undefeated. The Rams now prepare for a home game against the New York Giants.

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