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San Francisco 49ers defeat Los Angeles Rams 27-7 in Week 1

Yahoo Sports • 1 min read • Latest: Sep 13, 2026, 3:13 PM

Last updated Sep 13, 2026

San Francisco 49ers defeat Los Angeles Rams 27-7 in Week 1

Summary

The San Francisco 49ers opened their NFL season with a 27-7 victory over the Los Angeles Rams on Thursday, September 10. Quarterback Brock Purdy completed 25 of 34 passes for 205 yards, three touchdowns, and one interception. The 49ers offense totaled 174 rushing yards, while the offensive line allowed no sacks during the contest. Defensively, San Francisco limited the Rams to seven points, the lowest scoring output for Los Angeles during the tenure of quarterback Matthew Stafford. Linebacker Fred Warner recorded 11 tackles and a forced fumble to anchor the defensive performance. This victory occurred despite recent team controversies involving front office and roster personnel changes.

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By the Numbers

•The 49ers defeated the Rams 27-7 on September 10.
•Brock Purdy threw three touchdown passes and recorded 205 passing yards.
•The 49ers rushing attack produced 174 total yards.
•Fred Warner led the 49ers defense with 11 tackles and a forced fumble.
•The Rams offense managed only one touchdown in the game.

Latest Updates

3:13 PMYahoo Sports — The 49ers Shocked the NFL World by Upsetting the Rams

What they're saying

"
On Thursday, Sept. 10, the San Francisco 49ers shocked and surprised everyone in the NFL world. They upset the Los Angeles Rams 27-7 in their Week 1 matchup. Los Angeles came into the game as heavy favorites. Many around the league, including the media and fans, could not believe the dominance from the underdog 49ers. But […] The post The 49ers Shocked the NFL World by Upsetting the Rams appeared first on The Lead.
— Yahoo Sports

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Los Angeles Rams San Francisco 49ers NFL Football