San Francisco 49ers face multiple injury concerns ahead of season opener

Yahoo Sports1 min read • Latest: Aug 23, 2026, 2:16 AM

Last updated Aug 23, 2026

San Francisco 49ers face multiple injury concerns ahead of season opener
Summary

The San Francisco 49ers' injury woes continue to mount as the preseason nears its end. Key players listed as questionable include Christian Kirk (calf), Nick Martin (hamstring), and running back Jordan James (rib), among others. Tight end George Kittle is recovering from a torn Achilles, while Nick Bosa is progressing from an ACL injury. Coach Kyle Shanahan noted that all injured players are being monitored ahead of the regular season. With the team expected to travel to Melbourne for their opener against the Los Angeles Rams, their status will be closely watched.

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Status Watch
  • Christian Kirk and Nick Martin are questionable for the season opener.
  • George Kittle is recovering but aiming for the opener against the Rams.
  • Nick Bosa shows progress from his ACL injury.
  • Jordan James and Deommodore Lenoir have uncertain statuses due to injuries.
  • The 49ers' opening game will be in Melbourne, Australia.
Latest Updates
  • 2:16 AMYahoo SportsSan Francisco 49ers injury list: Ranking most concerning roster issues
What they're saying
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The San Francisco 49ers have been banged up. These are most concerning injuries they face.

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