San Francisco 49ers place Isaac Guerendo on reserve/PUP list

The San Francisco 49ers have placed running back Isaac Guerendo on the reserve/PUP list, meaning he will miss at least the first four games of the upcoming season. Guerendo remained sidelined throughout training camp following a pectoral injury sustained in late May. The move allows the organization to retain the running back without using one of their active roster spots or an Injured Reserve designation. The team opted for this path following the return of fellow running backs Christian McCaffrey, Kaelon Black, and Jordan James from August injuries. Under current NFL rules, Guerendo could have his 21-day practice window opened as early as after the second week of the season. The franchise continues to evaluate roster spots, with additional moves expected involving players like Kurtis Rourke and Brett Toth.

• 9:09 PMYahoo Sports — Isaac Guerendo to begin the season on the reserve/PUP