San Francisco 49ers prepare for season opener against Los Angeles Rams

The San Francisco 49ers open their 2026 NFL season against the Los Angeles Rams in Australia. This matchup follows a split season series in 2025, where the teams traded victories. San Francisco features a new offensive weapon in wide receiver Mike Evans, who joins the roster after 12 seasons with the Tampa Bay Buccaneers. Team availability remains a primary focus, with Nick Bosa managing knee tendonitis and George Kittle recovering from an Achilles tear. The 49ers also rely on rookie wide receiver De'Zhaun Stribling and rookie linebacker Jaden Dugger to contribute early in the season. Thursday’s game marks the first opportunity for the revamped roster to test its new personnel against a division rival.

• 8:35 PMYahoo Sports — 5 Questions with the Enemy: Asking a 49ers fan about what Mike Evans brings to SF’s offense