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49ers face injuries to Trent Williams and Deommodore Lenoir against Cardinals

Yahoo Sports • 1 min read • Latest: Sep 27, 2026, 11:45 PM

Last updated Sep 27, 2026

49ers face injuries to Trent Williams and Deommodore Lenoir against Cardinals

Summary

The San Francisco 49ers are playing against the Arizona Cardinals at Levi's Stadium. In the ongoing game, the 49ers, already without Nick Bosa, have lost star offensive tackle Trent Williams and cornerback Deommodore Lenoir. Williams suffered a potential head injury during a touchdown run by Christian McCaffrey, while Lenoir left the game after a helmet-to-helmet hit from teammate Fred Warner. The 49ers led early and maintained a narrow advantage as the fourth quarter progressed.

Source Links

Yahoo Sports

Status Watch

•The game is part of Week 3 NFL action on September 27.
•49ers have been managing injuries to key players throughout the game.
•Trent Williams and Deommodore Lenoir are both being evaluated for injuries.
•The 49ers are currently leading the Cardinals in a tightly contested matchup.
•Brock Purdy has over 250 passing yards and two touchdowns so far.

Latest Updates

11:45 PMYahoo Sports — 49ers news: Nick Bosa-less San Francisco loses Trent Williams, another star defender during Cardinals game

What they're saying

"
The San Francisco 49ers took on the Arizona Cardinals at Levi’s Stadium in Week 3 action that saw Mike Evans get carted to the locker room with a disconcerting injury. The 49ers, without Nick Bosa , also lost star offensive tackle Trent Williams and another defensive star during the game. Defensive back Deommodore Lenoir left the game according to […] The post 49ers news: Nick Bosa-less San Francisco loses Trent Williams, another star defender during Cardinals game appeared first on ClutchPoints
— Yahoo Sports

Related Teams & Leagues

Arizona Cardinals San Francisco 49ers NFL Football