Cardinals struggle in lopsided loss to Lions in Arizona

On October 11, 2026, the Arizona Cardinals suffered a 45-21 defeat at home against the Detroit Lions. The game started competitively, but the Cardinals' defense failed to contain Lions quarterback Jared Goff and running back Jahmyr Gibbs, allowing 412 total yards. Arizona's offense, playing without receiver Marvin Harrison Jr., was unable to sustain drives, resulting in poor performance from quarterback Jacoby Brissett. The loss marks the Cardinals' ongoing struggles under new head coach Mike LaFleur and general manager Monti Ossenfort, raising questions about potential changes within the organization.

• 12:12 AMYahoo Sports — Cardinals’ Woes Reach New Low in Blowout Loss to Lions