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Chargers prepare for regular season opener against the Cardinals on Sunday

Yahoo Sports • 1 min read • Latest: Sep 11, 2026, 4:17 AM

Last updated Sep 11, 2026

Chargers prepare for regular season opener against the Cardinals on Sunday
Summary

The Los Angeles Chargers open their 2026 NFL season at home against the Arizona Cardinals on Sunday, September 13. This game marks the debut of offensive coordinator Mike McDaniel, who replaces the team’s previous run-heavy system with a motion-oriented passing scheme. Justin Herbert will operate behind a reconstructed offensive line featuring newcomers at center and guard, while the defense transitions under new coordinator Chris O'Leary. The defensive unit faces an early challenge against Cardinals quarterback Jacoby Brissett, even as the team manages injuries at linebacker. Coaching staff decisions regarding target distribution among wide receivers and tight ends remain a focal point for the opening contest. Kickoff is scheduled for 1:25 PM PT at the Chargers' home venue.

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Status Watch
  • •Mike McDaniel debuts his motion-heavy offensive scheme for the Chargers.
  • •Jake Slaughter steps into the starting center role due to injury.
  • •Chris O'Leary implements a new defensive strategy against Jacoby Brissett.
  • •The game takes place on Sunday, September 13, at 1:25 PM PT.
  • •Denzel Perryman remains on injured reserve for the opening week.
Latest Updates
  • 4:17 AMYahoo Sports — 5 Chargers storylines to watch in season opener against the Cardinals
What they're saying
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The Chargers will kick off their 2026 NFL regular season at home against the Cardinals. Here are five key things to watch for during the game.

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