Chargers prepare for Sunday season opener against the Cardinals

The Los Angeles Chargers open their 2026 NFL season this Sunday against the Arizona Cardinals. This game marks the coaching debut of Chris O'Leary, who takes over as the defensive play caller following the departure of Jesse Minter. Chargers veterans Derwin James Jr. and Khalil Mack expressed public support for the new coordinator ahead of his first regular-season assignment. O'Leary stated he intends to treat the season as a developmental process, noting he gained valuable experience through the preseason games. The team enters the contest with a revamped roster on both sides of the ball, including an offensive unit led by Mike McDaniel. Los Angeles looks to begin the season with a win against an Arizona squad projected to finish among the bottom of the league standings.

• 6:56 PMYahoo Sports — Chargers' defense sends strong message ahead of Chris O'Leary's debut