Trey Mancini retires from MLB after colon cancer recovery

Yahoo Sports1 min read • Latest: Aug 18, 2026, 2:59 PM

Last updated Aug 18, 2026

Trey Mancini retires from MLB after colon cancer recovery
Summary

Trey Mancini announced his retirement from Major League Baseball on August 18, 2026, after a career that included a battle with colon cancer. After missing the entire 2020 season for treatment, Mancini returned to play four more seasons, including winning a World Series with the Houston Astros in 2022. He expressed deep gratitude to fans, teammates, and medical staff in his announcement on Instagram. Mancini also played briefly for the Los Angeles Angels earlier this season before deciding to retire.

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  • Mancini returned to MLB in 2021 after battling colon cancer.
  • He won the AL Comeback Player of the Year award in 2021.
  • Mancini was part of the 2022 World Series-winning Astros.
  • He played with the Angels this season before retiring.
  • Mancini thanked fans and medical staff in his retirement announcement.
Latest Updates
  • 2:59 PMYahoo SportsTrey Mancini, Orioles standout who returned after colon cancer, retires from MLB: 'I have immense gratitude'
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Trey Mancini returned to the majors after missing the 2020 MLB season due to colon cancer.

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