Padres score four runs in fifth inning to defeat Twins

The San Diego Padres secured a 6-2 victory over the Minnesota Twins on August 21, 2026, at Petco Park, opening their three-game series. A pivotal four-run inning in the fifth allowed pitcher Randy Vasquez to secure his win after seven innings pitched, where he allowed two runs and struck out three. Ty France led the Padres with a two-run home run and finished with three RBIs. Fernando Tatis Jr. and Luis Rengifo contributed with multiple hits as the Padres seek to continue their success in the series' next game tonight at 5:40 p.m.

• 2:15 PMYahoo Sports — Padres sweep Twins after another big inning
• 2:15 PMYahoo Sports — Padres rally to beat Twins
• 1:30 PMYahoo Sports — Big inning helps Padres drop Twins